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of the patients randomised to the chemotherapy arm, 48% crossed over and subsequently received treatment with pembrolizumab.
48% af de patienter, som var randomiseret til kemoterapi- armen, krydsede over og fik efterfølgende behandling med pembrolizumab.
the difference was not statistically significant, however more than half of the patients in the anastrozole alone arm crossed over to a herceptin containing regimen after progression of disease.
forskellen var ikke statistisk signifikant, men mere end halvdelen af patienterne i armen med kun anastrozol blev behandlet med herceptin efter sygdomsprogression.
altogether 45 out of 88 (51%) patients in the control arm crossed-over to achieve active treatment with catumaxomab.
i alt krydsede 45 ud af 88 (51 %) af patienterne i kontrolarmen over til at få aktiv behandling med catumaxomab.
94 (83.9%) patients randomised to the bat arm crossed over to ruxolitinib treatment at week 32 or after, limiting the comparison between the two arms after week 32.
94 (83,9%) patienter randomiseret til bat-armen krydsede over til ruxolitinib-behandling ved uge 32 eller senere, hvilket begrænser sammenligningen af de to arme efter uge 32.
a total of 59 out of 85 (69.4%) patients from the placebo arm crossed over to open-label sunitinib following disease progression or unblinding at study closure.
i alt 59 ud af 85 (69,4%) patienter fra placebo-gruppen fik ublindet sunitinib- behandling efter sygdomsprogression eller afblinding ved studieafslutning.