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further catalytic activation of 5'-dfur then occurs by thymidine phosphorylase (thypase).
den videre katalytiske aktivering af 5’-dfur sker derefter ved hjælp af thymidinfosforylase (thypase).
Last Update: 2017-04-26
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according to immunohistochemical studies, thymidine phosphorylase appears to be in large part localised in tumour stromal cells.
i henhold til immunohistokemiske studier synes thymidinfosforylase hovedsageligt lokaliseret i stromale tumorceller
Last Update: 2017-04-26
Usage Frequency: 6
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thymidine phosphorylase activity was measured and found to be 4 times greater in primary colorectal tumour than in adjacent normal tissue.
thymidinfosforylaseaktiviteten var 4 gange større i primært kolorektalt tumorvæv end i det tilstødende normale væv.
Last Update: 2017-04-26
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hypoglycaemia after fructose ingestion is caused by fructose 1phosphate inhibiting glycogenolysis at the phosphorylase level and gluconeogenesis at the mutant aldolase level.
hypoglykæmi efter indtag af fruktose forårsages af fruktose-1-fosfat, der hæmmer glykogenolyse på fosforylase-niveau og glukoneogense på mutant-aldolase-niveau.
Last Update: 2014-02-06
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in human cancer xenograft models capecitabine demonstrated a synergistic effect in combination with docetaxel, which may be related to the upregulation of thymidine phosphorylase by docetaxel.
i humane cancerxenotransplantationsmodeller har capecitabin vist en synergistisk effekt i kombination med docetaxel, som kan være relateret til docetaxels opregulering af thymidinfosforylase.
Last Update: 2017-04-26
Usage Frequency: 5
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phosphorylase in muscle. as glycogen reserves are depleted in prolonged fasting, so the vitamin is released from muscle, and made available for the synthesis of glucose from amino acids in the liver.
efterhånden som glycogenreserveme udtømmes ved langvarig faste, frigøres vitaminet fra muskelvævet og bliver tilgængeligt for syntese af glucose fra aminosyrer i leveren. imidlertid frigøres pyridoxalphosphat i
Last Update: 2014-02-06
Usage Frequency: 1
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at therapeutic concentrations febuxostat does not inhibit other enzymes involved in purine or pyrimidine metabolism, namely, guanine deaminase, hypoxanthine guanine phosphoribosyltransferase, orotate phosphoribosyltransferase, orotidine monophosphate decarboxylase or purine nucleoside phosphorylase.
ved terapeutiske koncentrationer hæmmer febuxostat ikke andre enzymer, der medvirker i purin- eller pyrimidinmetabolismen, dvs. guanin-deaminase, hypoxanthin- guanin-phosphoribosyltransferase, orotat-phosphoribosyltransferase, orotidinmonophosphat- decarboxylase eller purinnukleosid-phosphorylase.
Last Update: 2017-04-26
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the enzyme involved in the final conversion to 5-fu, thymidine phosphorylase (thypase), is found in tumour tissues, but also in normal tissues, albeit usually at lower levels.
enzymet thymidinfosforylase (thypase), som er involveret i den endelige omdannelse til 5-fu, findes i tumorvæv, men også i normalt væv, om end i lavere koncentrationer.
Last Update: 2017-04-26
Usage Frequency: 5
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