From professional translators, enterprises, web pages and freely available translation repositories.
7 conjugation to an inactive glucuronidated metabolite.
zidovudine wordt voornamelijk geëlimineerd via hepatische conjugatie tot een inactieve geglucuronideerde metaboliet.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
Warning: This alignment may be wrong.
Please delete it you feel so.
there is no impact on glucuronidated-zdv levels.
er is geen invloed op de geglucuronideerde zidovudine-spiegels.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
metabolites are then excreted in the bile as either free or glucuronidated metabolites.
aanvullende minder belangrijke metabole routes zijn n-dealkylering en hydrolyse.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
deferasirox is mainly glucuronidated by ugt1a1 and to a lesser extent ugt1a3.
deferasirox wordt voornamelijk geglucuronideerd door ugt1a1 en in mindere mate door ugt1a3.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
zidovudine is primarily eliminated by hepatic conjugation to an inactive glucuronidated metabolite.
zidovudine wordt primair geëlimineerd via hepatische conjugatie tot een inactieve geglucuronideerde metaboliet.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
elvitegravir undergoes primarily oxidative metabolism via cyp3a, and is secondarily glucuronidated via ugt1a1/3 enzymes.
elvitegravir ondergaat primair oxidatieve metabolisering via cyp3a en wordt secundair geglucuronideerd via ugt1a1/3-enzymen.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
dextromethorphan is rapidly metabolized by cyp2d6 to its primary metabolite, dextrorphan, which is rapidly glucuronidated and renally eliminated.
dextromethorfan wordt snel gemetaboliseerd door cyp2d6 tot de primaire metaboliet ervan, dextrorfan, dat snel wordt geglucuronideerd en renaal geëlimineerd.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
thus cytochrome p450 metabolism, glucuronide conjugation, and urinary excretion of glucuronidated metabolites represent the primary route of nevirapine biotransformation and elimination in humans.
dus cytochroom-p450- metabolisme, glucuronide-conjugatie en excretie in de urine van de geglucuronideerde metabolieten vormt de belangrijkste route van de biotransformatie en eliminatie van nevirapine bij mensen.
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
ambrisentan is glucuronidated via several ugt isoenzymes (ugt1a9s, ugt2b7s and ugt1a3s) to form ambrisentan glucuronide (13%).
ambrisentan wordt geglucuronideerd via diverse ugt-isoenzymen (ugt1a9s, ugt2b7s en ugt1a3s) om ambrisentan glucuronide (13%) te vormen.
Last Update: 2017-04-26
Usage Frequency: 2
Quality:
in both species difloxacin may be conjugated (glucuronidated or sulphated), desmethylated into sarafloxacin or oxidised into n-oxide-difloxacin.
bij beide diersoorten kan het difloxacine worden geconjugeerd (geglucuronideerd of gesulfateerd), gedemethyleerd tot sarafloxacine of geoxideerd tot n-oxide-difloxacine.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
ambrisentan also undergoes oxidative metabolism mainly by cyp3a4 and to a lesser extent by cyp3a5 and cyp2c19 to form 4-hydroxymethyl ambrisentan (21%) which is further glucuronidated to 4-hydroxymethyl ambrisentan glucuronide (5%).
ambrisentan ondergaat ook oxidatieve omzetting, hoofdzakelijk door cyp3a4 en in mindere mate door cyp3a5 en cyp2c19 om 4-hydroxymethyl ambrisentan (21%) te vormen, dat verder wordt geglucuronideerd tot 4-hydroxymethyl ambrisentanglucuronide (5%).
Last Update: 2017-04-26
Usage Frequency: 3
Quality: