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nasal bone hyperplasia of the ethmoid turbinates has been observed in the nasal cavity of rats treated with ambrisentan, at exposure levels 3-fold the clinical auc.
ninaluu hüperplaasiat on täheldatud rottidel, kellel saavutatud ambrisentaani ekspositsiooni väärtused olid 3 korda suuremad kliinilisest auc-st.
Last Update: 2017-04-26
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tissue plasma saliva blister fluid bronchial mucosa alveolar macrophages epithelial lining fluid maxillary sinus ethmoid sinus nasal polyps interstitial fluid female genital tract* * intravenous administration of a 1 10 h after administration 2 unbound concentration 3 from 3 h up to 36 h post dose 4 at the end of infusion
kude plasma sülg rakuvedelik bronhide limaskest alveolaarsed makrofaagid epiteliaalne vedelik Ülalõuasiinus etmoidaalne siinus nina polüübid interstitsiaalne vedelik naise genitaaltrakt *
Last Update: 2011-10-23
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