Results for hydroxylated translation from English to Icelandic

there are several hydroxylated metabolites of quinidine.
Það eru nokkur hýdroxýleruð umbrotsefni kínidíns.

a hydroxylated derivative was the most prominent metabolite in serum.
hydroxýltengd afleiða var mest áberandi umbrotsefnið í sermi.

both metabolites, are further metabolised forming a common hydroxylated acid.
bæði umbrotsefnin umbrotna frekar í venjulega hýrdoxýleraða sýru.

ketoconazole and erythromycin significantly inhibited the formation of nevirapine hydroxylated metabolites.
ketókónazól og erýtrómýcín hamla marktækt myndun hýdroxýleraðra umbrotsefna nevírapíns.

phenolic o-glucuronides of indacaterol and hydroxylated indacaterol were further prominent metabolites.
fenól o-glúkúróníð indacaterols og hýdroxýltengt indacaterol voru einnig áberandi umbrotsefni.

ethinyl estradiol is also metabolised to various hydroxylated products and their glucuronide and sulfate conjugates.
etinýlestradíól er einnig umbrotið í ýmis hýdroxýltengd efni og glúkóróníð- og súlfatsamtengingar þeirra.

oxidative metabolism catalysed by cyp3a4 and cyp2c8 leads to the formation of hydroxylated and dealkylated products.
oxunarumbrot sem hvötuð eru af cyp3a4 og cyp2c8 leiða til myndunar á hýdroxýleruðum og alkýlsviptum afurðum.

greater than 80 % of the radioactivity in urine was made up of glucuronide conjugates of hydroxylated metabolites.
meira en 80% af geislavirkninni í þvagi var vegna glúkúróníðsamtenginga hýdroxýleraðra umbrotsefna.

osaterone acetate is converted to its main, 15-hydroxylated metabolite, which is also pharmacologically active.
osateron acetat breytist í aðalumbrotsefnið, 15 beta hydroxýl umbrotsefni, sem er einnig lyfjafræðilega virkt.

nomegestrol acetate and its hydroxylated metabolites undergo extensive phase 2 metabolism to form glucuronide- and sulphate conjugates.
nomegestról acetat og hýdroxíltengd umbrotsefni þess verða fyrir miklu 2. stigs umbroti til að mynda súlfat- og glúkúróníðsamtenginga.

the formation of these hydroxylated metabolites is catalysed by cyp2c8, cyp3a4, and both cyp2c8 and cyp3a4 isoenzymes, respectively.
myndun þessara hýdroxýleruðu niðurbrotsefna er hvötuð af cyp2c8, cyp3a4, og bæði cyp2c8 og cyp3a4 ísóensímum.

hepatic metabolism of norelgestromin occurs and metabolites include norgestrel, which is largely bound to shbg, and various hydroxylated and conjugated metabolites.
norelgestromín umbrotnar í lifur og á meðal umbrotsefna eru norgestrel, sem er mikið bundið kynhormónabindandi glóbúlíni, og ýmis hýdroxýltengd og samtengd umbrotsefni.

based on in vitro studies, saquinavir is rapidly metabolised to a range of mono- and di-hydroxylated inactive compounds.
samkvæmt in vitro rannsóknum umbrotnar saquinavír hratt í mörg ein- og tvíhýdroxýleruð óvirk efnasambönd.

studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the cyp system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites.
rannsóknir hjá mönnum og in vitro rannsóknir á lifrarfrymisögnum (microsome) úr mönnum hafa sýnt að efavírenz umbrotnar fyrst og fremst fyrir tilstilli cyp-ferilsins yfir í hýdroxýleruð umbrotsefni með eftirfarandi glúkúróníðtengingu þessara hýdroxýleruðu umbrotsefna.

a hydroxylated metabolite of valdecoxib (via the cyp pathway) has been identified in human plasma that is active as a cox-2 inhibitor.
hýdroxýltengt umbrotsefni valdecoxibs (myndast eftir cyp ferli) hefur greinst í plasma manna og er virkt sem cox-2 hemill.

a diastereomer of the hydroxylated derivative, a n-glucuronide of indacaterol, and c- and n-dealkylated products were further metabolites identified.
fjölhverfa (diastereomer), hýdroxýltengdu afleiðunnar, n-glúkúróníð af indacateroli og c- og n-alkýlsvipt efnasambönd voru einnig meðal þeirra umbrotsefna sem greindust.

the major part is hydrogenated or hydroxylated in humans, the major metabolites being hydroxy-6-dexamethasone and dihydro-20-dexamethasone.
meginhlutinn er vetnistengdur eða vatnsrofinn hjá mönnum, helstu umbrotsefnin eru hýdroxý-6-dexametasón og díhýdró-20-dexametasón.

biotransformation and elimination: in vivo studies in humans and in vitro studies with human liver microsomes have shown that nevirapine is extensively biotransformed via cytochrome p450 (oxidative) metabolism to several hydroxylated metabolites.
umbrot og brotthvarf: in vivo rannsóknir á mönnum og in vitro rannsóknir á lifrarfrymisögnum manna hafa sýnt að nevírapín er mikið umbrotið fyrir tilstilli cýtókróm p450 (með oxun) umbrotsferlisins í nokkur hýdroxýleruð umbrotsefni.

following administration of a single oral [14c]canagliflozin dose to healthy subjects, 41.5%, 7.0%, and 3.2% of the administered radioactive dose was recovered in faeces as canagliflozin, a hydroxylated metabolite, and an o-glucuronide metabolite, respectively.
eftir inntöku staks skammt af [14c] kanaglíflózíni hjá heilbrigðum einstaklingum, 41,5%, 7,0% og 3,2% af gefnum geislamerktum skammti fannst í hægðum sem kanaglíflózín, hydroxylerað umbrotsefni og o-glucuroníð umbrotsefni, í sömu röð.