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for the server module versions of php, this happens only once when the web server is started.
the configuration file (called php3.ini in php 3.0, and simply php.ini as of php 4.0) is read when php starts up. for the server module versions of php, this happens only once when the web server is started. for the cgi and cli version, it happens on every invocation.
make sure that the sesam oml plam library and sesam configuration file are readable by the user id running the web server.
because of limitations of the bs2000 process model, the driver can be loaded only after the apache server has forked off its server child processes. this will slightly slow down the initial sesam request of each child, but subsequent accesses will respond at full speed.