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tpo-r-agonistit ovat kasvutekijöitä, jotka aktivoivat trombopoieettisen progenitorisolun kasvua ja erilaistumista ja trombosyyttien muodostumista.
tpo-r agonists are growth factors that lead to thrombopoietic progenitor cell expansion, differentiation and platelet production.
Last Update: 2017-04-26
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romiplostiimin farmakokinetiikkaan kuului kohdemekanismin kautta välittyvä ("target-mediated") poistuma, joka välittyy todennäköisesti trombosyyttien ja muiden trombopoieettisen linjan solujen, kuten megakaryosyyttien, tpo-reseptorien kautta.
the pharmacokinetics of romiplostim involved target-mediated disposition, which is presumably mediated by tpo receptors on platelets and other cells of the thrombopoietic lineage such as megakaryocytes.
Last Update: 2017-04-26
Usage Frequency: 3
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