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Η νιµεσουλίδη αναστέλλει το cyp2c9.
ear and labyrinth disorders cardiac disorders vascular disorders
Last Update: 2011-10-23
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Ιστορικό ηπατοτοξικών αντιδράσεων στη νιµεσουλίδη.
history of hypersensitivity reactions (e. g. bronchospasm, rhinitis, urticaria) in response to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
Last Update: 2011-10-23
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Επιδράσεις άλλων φαρµάκων στη νιµεσουλίδη:
there have been isolated reports of renal failure in neonates born to women taking nimesulide in late pregnancy.
Last Update: 2011-10-23
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Η νιµεσουλίδη απορροφάται καλώς όταν δίδεται από το στόµα.
6.6 instructions for use/ handling
Last Update: 2011-10-23
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Αυτοί οι ασθενείς δεν θα πρέπει να επανεκτίθενται στη νιµεσουλίδη.
in vitro studies have shown displacement of nimesulide from binding sites by tolbutamide, salicylic acid and valproic acid.
Last Update: 2011-10-23
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Γνωστή υπερευαισθησία στη νιµεσουλίδη ή σε κάποιο από τα έκδοχα των προϊόντων.
patients receiving warfarin or similar anticoagulant agents or acetylsalicylic acid have an increased risk of bleeding complications, when treated with.
Last Update: 2011-10-23
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Γαλουχία ∆εν είναι γνωστό εάν η νιµεσουλίδη απεκκρίνεται στο µητρικό γάλα.
hepatitis fulminant hepatitis (including fatal cases) jaundice cholestasis
Last Update: 2012-04-11
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Εάν εµφανισθεί γαστρεντερική αιµορραγία ή έλκος, η νιµεσουλίδη θα πρέπει να διακοπεί.
the plasma concentrations of drugs that are substrates of this enzyme may be increased when are used concomitantly.
Last Update: 2011-10-23
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cpmp/ 3086/ 03- rev. 1 Επιδράσεις άλλων φαρµάκων στη νιµεσουλίδη:
cpmp/ 3086/ 03-rev.1
Last Update: 2011-10-23
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Σε µελέτες τοξικότητας επαναλαµβανόµενης δόσης η νιµεσουλίδη έδειξε γαστρεντερική, νεφρική και ηπατική τοξικότητα.
qualitative and quantitative composition each suppository contains 100mg or 200mg nimesulide.
Last Update: 2011-10-23
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Η νιµεσουλίδη απεκκρίνεται κυρίως µε τα ούρα (περίπου 50% της χορηγηθείσας δόσης).
nimesulide is excreted mainly in the urine (approximately 50% of the administered dose).
Last Update: 2012-04-11
Usage Frequency: 2
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Κάθε φακελάκι και κάθε δισκίο περιέχει 400mg νιµεσουλίδη- β- κυκλοδεξτρίνη, που αντιστοιχούν σε 100mg νιµεσουλίδης.
patients who experience symptoms compatible with hepatic injury during treatment with (e.g. anorexia, nausea, vomiting, abdominal pain, fatigue, dark urine) or patients who develop abnormal liver function tests should have treatment discontinued.
Last Update: 2011-10-23
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Η νιµεσουλίδη µεταβολίζεται εκτενώς στο ήπαρ ακολουθώντας διάφορες οδούς, περιλαµβανοµένων των ινσοενζύµων (cyp) 2c9 του κυτοχρώµατος Ρ450.
nimesulide is extensively metabolised in the liver following multiple pathways, including cytochrome p450 (cyp) 2c9 isoenzymes.
Last Update: 2012-04-11
Usage Frequency: 2
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Ενήλικες: ∆ισκία 400mg νιµεσουλίδη- β- κυκλοδεξτρίνη, κοκκία 400mg νιµεσουλίδη- β- κυκλοδεξτρίνη:
in patients with renal or cardiac impairment, caution is required since the use of may result in deterioration of renal function.
Last Update: 2011-10-23
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100 mg ή 200mg υπόθετα νιµεσουλίδης:
in patients with renal or cardiac impairment, caution is required since the use of may result in deterioration of renal function.
Last Update: 2011-10-23
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