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norbuprenorfina
nd: nestanoveno.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
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auc: ↓ 50% norbuprenorfina:
auc: ↓ 50% norbuprenorfin:
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
norbuprenorfina metaboliti glucuronidi
buprenorfin, norbuprenorfin, metabolity glukuronidů
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
buprenorfina ↑ 1.67 ↑ 1.37 ↑ 1.69 norbuprenorfina ↑ 2.05 ↑ 1.61 ↑ 2.01
10 dávka, (atazanavir 300 mg qd s ritonavirem 100 mg qd)
Last Update: 2011-10-23
Usage Frequency: 4
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• inibitori dell’ enzima cyp3a4: uno studio di interazione tra buprenorfina e ketoconazolo (un potente inibitore del cyp3a4), ha evidenziato un aumento sia del cmax sia dell' auc (area sotto la curva) di buprenorfina (rispettivamente 70% and 50% circa) e, in misura leggermente inferiore, di norbuprenorfina.
• inhibitory cyp3a4: studie interakce buprenorfinu s ketokonazolem (účinným inhibitorem cyp3a4) ukázaly zvýšené cmax a auc (plocha pod křivkou) buprenorfinu (přibližně o 70%, respektive 50%) a v menší míře norbuprenorfinu.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
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