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mutazione del gene janus kinase 2
janus kinase 2 mutation
Last Update: 2014-12-08
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la nelarabina è rapidamente demetilata dalla adenosin deaminasi (ada) ad ara-g e poi fosforilata intracellularmente dalla deossiguanosina kinasi e dalla deossicitidina kinasi al suo metabolita 5’-monofosfato.
nelarabine is rapidly demethylated by adenosine deaminase (ada) to ara-g and then phosphorylated intracellularly by deoxyguanosine kinase and deoxycytidine kinase to its 5’-monophosphate metabolite.
Last Update: 2017-04-26
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