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dazniausiai pastebti gimti trkumai: kiskio lpa, sirdies ir kraujagysli sistemos anomalijos bei smegen defektas.
the risk of birth defect is increased by factor 2 to 3 in the offspring of mothers treated with an antiepileptic medication.the most frequently reported are cleft lip, cardiovascular malformations and neural tube defect.
Last Update: 2008-03-04
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vaistus nuo epilepsijos vartojanci moter vaikams gimt trkum rizika padidja 23 kartus.dazniausiai16 pastebti gimti trkumai: kiskio lpa, sirdies ir kraujagysli sistemos anomalijos bei smegen defektas.
15 advice regarding possible effects of zonegran on the foetus and the risk should be discussed with the patient in relation to the benefits before starting treatment.the risk of birth defect is increased by factor 2 to 3 in the offspring of mothers treated with an antiepileptic medication.the most frequently reported are cleft lip, cardiovascular malformations and neural tube defect.
Last Update: 2008-03-04
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poveikis triusi raidai: padaugjo kiskio lpos atvej, kai ekspozicija plazmoje buvo mazdaug tokia pati, kaip ligonio organizme, bei kiskio lpos ir vilko gomurio atvej, kai ekspozicija plazmoje buvo 2, 7 karto didesn uz t, kuri bna ligonio organizme.
in rabbits, developmental effects consisted of increased incidence of cleft lip at plasma exposure levels approximately equal to that observed in clinic, and cleft lip and cleft palate at plasma exposure levels 2.7-fold higher than is observed in clinic.
Last Update: 2008-03-04
Usage Frequency: 3
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