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il- 6 este o citokină proinflamatorie pleiotropă, produsă de o varietate de tipuri de celule incluzând celulele t şi b, monocite şi fibroblaste.
il-6 is a pleiotropic pro-inflammatory cytokine produced by a variety of cell types including t- and b-cells, monocytes and fibroblasts.
anakinra inhibă răspunsurile generate in vitro de il-1, inclusiv inducerea oxidului nitric şi a prostaglandinei e2 şi / sau sinteza colagenazei de către celulele sinoviale, fibroblaste şi condrocite.
anakinra inhibits responses elicited by il-1 in vitro, including the induction of nitric oxide and prostaglandin e2 and/or collagenase production by synovial cells, fibroblasts, and chondrocytes.
interleukina-6 este o citokină proinflamatorie pleiotropă produsă de o varietate de tipuri de celule, inclusiv celulele t și celulele b, limfocite, monocite și fibroblaste, precum şi celulele maligne.
interleukin-6 is a pleiotropic pro-inflammatory cytokine produced by a variety of cell types including t-cells and b-cells, lymphocytes, monocytes and fibroblasts, as well as malignant cells.
de asemenea, inhibă şi receptorul factorului de creştere derivat plachetar (pdgf) şi receptorul factorului de creştere fibroblastic (fgfr3).
it also inhibits the platelet derived growth factor (pdgf) receptor and the fibroblast growth factor receptor (fgfr3).