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in the elderly, alcohol and benzodiazepines are the most commonly abused substances, and the elderly population is more susceptible to benzodiazepine withdrawal syndrome and delirium than are younger patients.
in the elderly, alcohol and benzodiazepines are the most commonly abused substances, and the elderly population is more susceptible to benzodiazepine withdrawal syndrome and delirium than are younger patients.
Last Update: 2016-03-03
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the withdrawal syndrome from benzodiazepines can range from a mild and short-lasting syndrome to a prolonged and severe syndrome.
the withdrawal syndrome from benzodiazepines can range from a mild and short-lasting syndrome to a prolonged and severe syndrome.
Last Update: 2016-03-03
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==epidemiology==research studies have come to different conclusions on the number of therapeutic dose users who develop a physical dependence and withdrawal syndrome.
==epidemiology==research studies have come to different conclusions on the number of therapeutic dose users who develop a physical dependence and withdrawal syndrome.
Last Update: 2016-03-03
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tolerance and the resultant withdrawal syndrome may be due to alterations in gene expression, which results in long-term changes in the function of the gabaergic neuronal system.
tolerance and the resultant withdrawal syndrome may be due to alterations in gene expression, which results in long-term changes in the function of the gabaergic neuronal system.
Last Update: 2016-03-03
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severe withdrawal syndromes can occur from these low doses of benzodiazepines even after gradual dose reduction.
severe withdrawal syndromes can occur from these low doses of benzodiazepines even after gradual dose reduction.
Last Update: 2016-03-03
Usage Frequency: 1
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the committee found that the regular use of benzodiazepines causes the development of dependence characterized by tolerance to the therapeutic effects of benzodiazepines and the development of the benzodiazepine withdrawal syndrome including symptoms such as anxiety, apprehension, tremors, insomnia, nausea, and vomiting upon cessation of benzodiazepine use.
the committee found that the regular use of benzodiazepines causes the development of dependence characterized by tolerance to the therapeutic effects of benzodiazepines and the development of the benzodiazepine withdrawal syndrome including symptoms such as anxiety, apprehension, tremors, insomnia, nausea, and vomiting upon cessation of benzodiazepine use.
Last Update: 2016-03-03
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===legal implications===negligent management of the benzodiazepine withdrawal syndrome has led to some doctors' being brought before the general medical council in the uk, for example, for stopping sleeping tablets abruptly or reducing anxiolytics too quickly, failure to initiate replacement therapy (e.g., equivalent dose of diazepam), failure to increase dosage to alleviate severe withdrawal effects, and failure to warn the patient of the possibility of withdrawal symptoms, having led to a finding by the gmc of negligence against one doctor.
===legal implications===negligent management of the benzodiazepine withdrawal syndrome has led to some doctors' being brought before the general medical council in the uk, for example, for stopping sleeping tablets abruptly or reducing anxiolytics too quickly, failure to initiate replacement therapy (e.g., equivalent dose of diazepam), failure to increase dosage to alleviate severe withdrawal effects, and failure to warn the patient of the possibility of withdrawal symptoms, having led to a finding by the gmc of negligence against one doctor.
Last Update: 2016-03-03
Usage Frequency: 1
Quality:
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