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glukokortikoidreceptorer
glucocorticoid receptor
Last Update: 2014-12-09
Usage Frequency: 6
Quality:
i allmäntoxikologiska studier hade de flesta fynden samband med ulipristalacetats verkningsmekanism som modulator för progesteron- och glukokortikoidreceptorer, och antiprogesteronaktivitet observerades vid exponeringar motsvarande terapeutiska halter.
most findings in general toxicity studies were related to its mechanism of action as a modulator of progesterone and glucocorticoid receptors, with antiprogesterone activity observed at exposures similar to therapeutic levels.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
i allmäntoxikologiska studier hade de flesta fynden samband med ulipristalacetats verkningsmekanism för progesteronreceptorer (och vid högre koncentrationer för glukokortikoidreceptorer) och antiprogesteronaktivitet observerades vid exponeringar motsvarande terapeutiska nivåer.
most findings in general toxicity studies were related to its action on progesterone receptors (and at higher concentrations on glucocorticoid receptors), with antiprogesterone activity observed at exposures similar to therapeutic levels.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
flutikasonfuroat är en syntetisk trifluorinerad kortikosteroid som har mycket hög affinitet till glukokortikoidreceptorn och har en potent antiinflammatorisk effekt.
fluticasone furoate is a synthetic trifluorinated corticosteroid that possesses a very high affinity for the glucocorticoid receptor and has a potent anti-inflammatory action.
Last Update: 2017-04-26
Usage Frequency: 3
Quality: