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vid administrering av en dygnsdos på 2, 5 ml per kilo kroppsvikt (ca 15 x rekommenderad klinisk maximidos) till dräktiga kaniner under organogenesen konstaterades en toxisk effekt som omfattande hona och foster jämte dilatation av hjärnventriklarna som varierade från lätt till ansenlig hos det växande fostret.
in pregnant rabbits exposed to daily doses of 2.5 ml/ kg (approximately 15 x the maximum recommended clinical dose) during organogenesis, maternal toxicity and embryo-foetal toxicity including a slight to extreme dilation of ventricles in the brain of developing rabbit embryos was observed.
Last Update: 2012-04-11
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