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cellular
celičaste strukture
Dernière mise à jour : 2014-11-21
Fréquence d'utilisation : 5
Qualité :
the exact mechanisms by which lumacaftor improves cellular processing and trafficking of f508del-cftr and ivacaftor potentiates f508del-cftr are not known.
natančni mehanizmi, s katerimi lumakaftor izboljša celično procesiranje in transport f508del-cftr in ivakaftor ojačuje f508del-cftr, niso znani.
lumacaftor is a cftr corrector that acts directly on f508del-cftr to improve its cellular processing and trafficking, thereby increasing the quantity of functional cftr at the cell surface.
lumakaftor je popravljalec cftr, ki deluje neposredno na f508del-cftr in izboljša njegovo celično procesiranje in transport, s čimer zveča količino funkcionalnega cftr na površini celice.