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eelravim
prodrug

klopidogreel on eelravim.
clopidogrel is a prodrug.

ravicti on pba eelravim.
ravicti is a pro-drug of pba.

parekoksiib on valdekoksiibi eelravim.
parecoxib is a prodrug of valdecoxib.

paliperidoonpalmitaat on paliperidooni palmitaatestrist eelravim.
paliperidone palmitate is the palmitate ester prodrug of paliperidone.

ivemendi toimeaine fosaprepitant on aprepitandi eelravim.
the active substance in ivemend, fosaprepitant, is a ‘prodrug’ of aprepitant.

naatriumfenüülbutüraat on eelravim ja metaboliseerub kiiresti fenüülatsetaadiks.
sodium phenylbutyrate is a pro-drug and is rapidly metabolised to phenylacetate.

sofosbuviir on nukleotiidi eelravim, mida metaboliseeritakse ulatuslikult.
sofosbuvir is a nucleotide prodrug that is extensively metabolised.

fosamprenaviir on amprenaviiriks nimetatud ravimi „ eelravim ”.
fosamprenavir is a ‘ pro-drug ’ of the medicine amprenavir.

toimemehhanism nepafenak on mittesteroidne põletikuvastane ja valuvaigistav eelravim.
mechanism of action nepafenac is a non-steroidal anti-inflammatory and analgesic prodrug.

tenofoviiralafenamiid on tenofoviiri eelravim, mis muutub organismis tenofoviiriks.
tenofovir alafenamide is a ‘prodrug’ of tenofovir, meaning that it is converted into the active substance tenofovir in the body.

dabigatraaneteksilaat on madalmolekulaarne eelravim, millel puudub farmakoloogiline toime.
dabigatran etexilate is a small molecule prodrug which does not exhibit any pharmacological activity.

intravenoosselt manustatud aprepitandi eelravim fosaprepitant muudetakse kiiresti aprepitandiks.
fosaprepitant, a prodrug of aprepitant, when administered intravenously is rapidly converted to aprepitant.

benasepriil on eelravim, mis muudetakse organismis aktiivseks toimeaineks benaseprilaadiks.
benazepril is a prodrug, a substance that is converted to benazeprilat in the body.

benasepriilvesinikkloriid on eelravim, mis hüdrolüüsub in vivo aktiivseks metaboliidiks, benaseprilaadiks.
benazepril hydrochloride is a prodrug hydrolysed in vivo to its active metabolite, benazeprilat.

telziri toimeaine fosamprenaviir on eelravim, mis muundub organismis proteaasiinhibiitoriks amprenaviiriks.
the active substance in telzir, fosamprenavir, is a ‘prodrug’ of the protease inhibitor amprenavir, which means that it is converted into amprenavir in the body.

veenisiseselt manustatud fosaprepitant (aprepitandi eelravim) muudetakse kiiresti aprepitandiks.
fosaprepitant, a prodrug of aprepitant, when administered intravenously is rapidly converted to aprepitant.

prasugreel on eelravim ja metaboliseerub in vivo kiiresti aktiivseks metaboliidiks ja inaktiivseteks metaboliitideks.
prasugrel is a prodrug and is rapidly metabolised in vivo to an active metabolite and inactive metabolites.

tenofoviirdisoproksiilfumaraat on vesilahustuv ester, eelravim, mis muudetakse in vivo kiiresti tenofoviiriks ja formaldehüüdiks.
tenofovir disoproxil fumarate is a water soluble ester prodrug which is rapidly converted in vivo to tenofovir and formaldehyde.

indoksakarb on eelravim, mille farmakodünaamiliste toimete avaldumiseks on vajalik bioaktiviseerumine ainele tundlike putukate ensüümide abil.
indoxacarb is a pro- drug that requires bioactivation by enzymes in susceptible insects to exert its pharmacodynamic effects.