Hai cercato la traduzione di sapropterina da Croato a Inglese

hrana ima utjecaj na brzinu i stupanj apsorpcije sapropterina.
the rate and extent of absorption of sapropterin is influenced by food.

u pretkliničkim ispitivanjima nisu opaženi učinci sapropterina na mušku i žensku plodnost.
in preclinical studies, no effects of sapropterin on male and female fertility were observed.

jedna tableta sadrži 100 mg sapropterindiklorida (što odgovara 77 mg sapropterina).
each tablet contains 100 mg of sapropterin dihydrochloride (equivalent to 77 mg of sapropterin).

jedna tableta za oralnu otopinu sadrži 100 mg sapropterindiklorida (što odgovara 77 mg sapropterina).
each soluble tablet contains 100 mg of sapropterin dihydrochloride (equivalent to 77 mg of sapropterin).

kod štakora, nakon intravenskog davanja radioaktivno označenog sapropterina, pokazalo se da se radioaktivnost distribuira u fetusima.
in rats, following intravenous radiolabeled sapropterin administration, radioactivity was found to distribute in foetuses.

slučajevi konvulzija, pogoršanja konvulzija, povećane podražljivosti i iritabilnosti zamijećeni su tijekom istovremene primjene levodope i sapropterina kod pacijenata s manjkom bh4.
cases of convulsion, exacerbation of convulsion, increased excitability and irritability have been observed during co- administration of levodopa and sapropterin in bh4-deficient patients.

analiza populacijske farmakokinetike sapropterina u bolesnika u dobi od rođenja do 49 godina pokazala je da je tjelesna težina jedina kovarijanca koja znatno utječe na njegov klirens ili volumen distribucije.
population pharmacokinetic analysis of sapropterin including patients from birth to 49 years of age showed that body weight is the only covariate substantially affecting clearance or volume of distribution.

slučajevi konvulzija, pogoršanja konvulzija, povećane podražljivosti i iritabilnosti zamijećeni su tijekom istovremene primjene levodope i sapropterina kod pacijenata s manjkom bh4 (vidjeti dio 4.5).
cases of convulsion, exacerbation of convulsion, increased excitability and irritability have been observed during co- administration of levodopa and sapropterin in bh4-deficient patients (see section 4.5).

apsorpcija sapropterina je veća nakon jako masnog, visoko kaloričnog obroka nego nakon gladovanja, što u prosjeku rezultira s 40-85% većom maksimalnom koncentracijom u krvi, postignutom 4 do 5 sati nakon uzimanja lijeka.
the absorption of sapropterin is higher after a high-fat, high-calorie meal as compared to fasting, resulting, in average, in 40-85% higher maximum blood concentrations achieved 4 to 5 hours after administration.