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la subiecţii sănătoşi, prasugrel a scăzut cu 23% expunerea la hidroxibupropion, un metabolit al bupropionei mediat pe calea cyp2b6.
in healthy subjects, prasugrel decreased exposure to hydroxybupropion, a cyp2b6-mediated metabolite of bupropion, by 23%.
最終更新： 2017-04-26
使用頻度： 3
品質：
bupropion: la voluntarii sănătoşi, la starea de echilibru, asc şi cmax ale bupropionului şi ale metabolitului său activ, hidroxibupropion, au scăzut cu aproximativ 50% atunci când a fost administrat concomitent cu lopinavir/ ritonavir capsule 400/ 100 mg de două ori pe zi.
8 bupropion: in healthy volunteers, the auc and cmax of bupropion and of its active metabolite, hydroxybupropion, were decreased by about 50% when co-administered with lopinavir/ ritonavir capsules 400/ 100 mg twice daily at steady-state.
最終更新： 2012-04-11
使用頻度： 6
品質：