검색어: busulfana (크로아티아어 - 영어)

doza busulfana (mg /kg)
busulfan dose (mg/kg)

ispitivana je farmakokinetika busulfana.
the pharmacokinetics of busulfan has been investigated.

nakon razrjeđivanja: 1 ml otopine sadrži 0,5 mg busulfana.
after dilution: 1 ml of solution contains 0.5 mg of busulfan

dostupni podaci dobiveni na životinjama podržavaju karcinogeni potencijal busulfana.
the available data in animals support the carcinogenic potential of busulfan.

nakon razrjeđivanja 1 ml otopine za infuziju sadrži 0,5 mg busulfana.
after dilution, 1 ml of solution for infusion contains 0.5 mg of busulfan.

mora se postići konačna koncentracija od otprilike 0,5 mg/ml busulfana.
a final concentration of approximately 0.5 mg/ml busulfan should be achieved.

jedan ml koncentrata sadrži 6 mg busulfana (60 mg u 10 ml).
one ml of concentrate contains 6 mg of busulfan (60 mg in 10 ml).

posebna pozornost potrebna je kada se preporučena doza busulfana daje bolesnicima s anamnezom napadaja.
special caution should be exercised when administering the recommended dose of busulfan to patients with a history of seizures.

intravenska primjena busulfana na miševima značajno je povećala učestalost tumora timusa i jajnika.
intravenous administration of busulfan to mice significantly increased the incidences of thymic and ovarian tumours.

dokazano je povećanje izloženosti busulfanu proporcionalno dozi nakon intravenoznog busulfana do 1 mg/kg.
the dose proportional increase of busulfan exposure was demonstrated following intravenous busulfan up to 1 mg/kg.

d: doza busulfana (vidjeti sažetak opisa svojstava lijeka, dio 4.2)
d: dose of busulfan (see spc section 4.2)

preostali lijek ne smije se ispirati u cijevima za primjenu jer brza infuzija busulfana nije testirana i ne preporučuje se.
the residual medicinal product must not be flushed in the administration tubing as rapid infusion of busulfan has not been tested and is not recommended.

nije zabilježen učinak dobi na klirens busulfana na temelju dostupnih podataka o intravenskom busulfanu u bolesnika iznad 60 godina.
no age effect on busulfan clearance was evidenced from available intravenous busulfan data in patients over 60 years.

antiemetike treba primijeniti prije prve doze busulfana i nastaviti s njihovom primjenom prema dogovorenom rasporedu u skladu s lokalnom praksom.
antiemetics should be administered prior to the first dose of busulfan and continued on a fixed schedule according to local practice through its administration.

busilvex se sastoji od koncentrata za otopinu za infuziju i isporučuje se u bezbojnim staklenim bočicama, svaka bočica sadrži 60 mg busulfana.
busilvex consists of a concentrate for solution for infusion and is supplied in colourless glass vials, each vial containing 60 mg of busulfan.

busulfan fresenius kabi se sastoji od koncentrata za otopinu za infuziju i isporučuje se u bezbojnim staklenim bočicama, svaka bočica sadrži 60 mg busulfana.
busulfan fresenius kabi consists of a concentrate for solution for infusion and is supplied in colourless glass vials, each vial containing 60 mg of busulfan.

količina otapala mora biti 10 puta veća od volumena lijeka busulfan fresenius kabi što će osigurati konačnu koncentraciju busulfana od približno 0,5 mg/ml.
the quantity of the diluent must be 10 times the volume of busulfan fresenius kabi ensuring the final concentration of busulfan remains at approximately 0.5 mg/ml.

količina otapala mora biti 10 puta veća od volumena lijeka busulfan fresenius kabi, što će osigurati konačnu koncentraciju busulfana od približno 0,5 mg/ml.
the quantity of the diluent must be 10 times the volume of the busulfan fresenius kabi ensuring the final concentration of busulfan remains at approximately 0.5 mg/ml.

analiza podataka populacijskom farmakokinetičkom metodom pokazala je da ne postoje razlike u klirensu intravenskog busulfana između liječenja koje se temelji na fenitoinu i klonazepamu pa su stoga postignute slične izloženosti plazme busulfanu bez obzira na vrstu profilaktične terapije napadaja.
the analysis of data through a population pharmacokinetic method indicated no difference on intravenous busulfan clearance between phenytoin and clonazepam based therapy and therefore similar busulfan plasma exposures were achieved whatever the type of seizure prophylaxis.

za paracetamol je opisano da smanjuje razinu glutationa u krvi i tkivima pa stoga može smanjiti klirens busulfana kada se upotrebljava u kombinaciji (vidjeti dio 4.4).
paracetamol is described to decrease glutathione levels in blood and tissues, and may therefore decrease busulfan clearance when used in combination (see section 4.4).