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upon resolution of the reaction, reinitiating the infusion at a lower infusion rate and therapeutic administration of antihistamines, acetaminophen, and corticosteroids may be considered.
når reaktionen ophører, kan det overvejes at genoptage infusionen med langsommere hastighed, samt at behandle med antihistaminer, paracetamol og kortikosteroider.
do not report hepatitis or jaundice that results from exposure to hepatotoxins (alcoholic or acetaminophen-induced hepatitis, etc.)
hepatitis eller gulsot, som skyldes eksponering for hepatotoksiner (alkoholisk eller paracetamolinduceret hepatitis, etc.) anmeldes ikke
of a panel of potential comedications (acetaminophen, aciclovir, allopurinol, amphotericin, cytarabine, erythromycin, fluconazole, hydroxyurea, norfloxacin, penicillin v) only erythromycin (ic50 50 µm) and fluconazole (ic50 118 µm) showed inhibition of imatinib metabolism which could have clinical relevance.
af en række potentielle samtidigt administrerede lægemidler (acetaminophen, acicolvir, allopurinol, amphotericin, cytarabin, erythromycin, fluconazole, hydroxyurea, norfloxacin, penicillin v) viste kun erythromycin (ic50 50 µm) og fluconazol (ic50 118 µm) hæmning af imatinib- metabolismen i et omfang der kunne have klinisk betydning.