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cytogenetic abnormalities
anormalitajiet ċitoġenetiċi

cytogenetic response (%)
rispons Ċitoġenetiku (%)

cumulative cytogenetic responsea
rispons Ċitoġeniku kumulattiva

2 cytogenetic response criteria:
² kriterji għar-risponsijiet ċitoġenetiċi:

major cytogenetic response complete
rispons ċitoġenetiku maġġuri2 komplet 3

cytogenetic response within 12 months
rispons ċitoġeniku fi żmien 12-il xahar

cytogenetic response major response n (%)
rispons ċitoġenetiku n (%) rispons maġġuri

complete nel return to cp cytogenetic response (%)
nel marru lura għall- cp

three patients had cytogenetic abnormalities at baseline.
tliet pazjenti kellhom anormalitajiet ċitoġenetiċi fil-linja bażi.

cytogenetic analyses in first line b-cll patients:
13 analiżi Ċitoġenika għal pazjenti b’ b- cll ikkurati għall- ewwel darba:

cytogenetic abnormalities are known to occur in saa patients.
hu magħruf li anormalitajiet ċitoġenetiċi jseħħu f’pazjenti b’saa.

baseline cytogenetic (fish) data were available for 209 patients.
dejta ċitoġenika tal-linja bażi (fish) kienet disponibbli għal 209 pazjenti.

failure to achieve complete cytogenetic response (ccyr) by week 12
in-nuqqas li jinkiseb rispons ċitoġeniku sħiħ (ccyr) sa ġimgħa 12

cytogenetic abnormalities were evaluated in 117 of the total population of 176patients.
abnormalitajiet ċitoġenetiċi kienu evalwati f’117 mill-popolazzjoni kollha ta’

cytogenetic abnormalities were evaluated in 117 of the total population of 176 patients.
anormalitajiet ċitoġenetiċi kienu evalwati f’117 mill-popolazzjoni kollha ta’ 176 pazjent.

slamf7 is highly expressed on multiple myeloma cells independent of cytogenetic abnormalities.
slamf7 tinstab fi kwantità għolja f’ċelloli tal-majeloma multipla indipendentement minn anormalitajiet ċitoġenetiċi.

haematologic and cytogenetic responses were assessed by the investigator and by the irc with similar results.
ir-risponsi ematoloġiċi u ċitoġenetiċi ġew evalwati mill-investigatur u mill-irc b’riżultati simili.

the treatment should not be initiated when the patients have existing cytogenetic abnormalities of chromosome 7.
it-trattament m’għandux jinbeda meta l-pazjenti għandhom anormalitajiet ċitoġeniċi eżistenti tal-kromożomu 7.

eleven patients achieved rapid chr; ten had complete resolution of cytogenetic abnormalities and a decrease
Ħdax il- pazjent kisbu chr malajr, għaxra kellhom fejqan għall- kollox mill- anormalitajiet ċitoġenetiċi u tnaqqis jew tneħħija tat- transcripts ta ’ fużjoni kif imkejjla mill- rt- pcr.

all patients achieved complete haematological response, complete cytogenetic response and/or complete molecular response.
il-pazjenti kollha kellhom rispons ematoloġiku, rispons ċitoġenetiku u/jew rispons molekulari sħiħ.