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primary processes such as photosynthesis and biosynthesis;
tādiem primāriem procesiem kā fotosintēze un biosintēze;
Son Güncelleme: 2014-11-14
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ferrochelatase) involved in haemoglobin biosynthesis in tumour cells.
lielāku 5- ala uzņemšanu
Son Güncelleme: 2011-10-23
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doripenem exerts its bactericidal activity by inhibiting bacterial cell wall biosynthesis.
doripenēma baktericīdo darbību nodrošina tā inhibējošā iedarbība uz baktēriju šūnu sieniņu biosintēzi.
Son Güncelleme: 2017-04-26
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this results from the selective inhibition of the cyp17 enzyme required for androgen biosynthesis.
to nosaka androgēnu biosintēzei nepieciešamā enzīma cyp17 selektīva inhibīcija.
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macrolides inhibit bacterial protein biosynthesis by binding to the 50s ribosomal subunit and by preventing peptide chain elongation.
makrolīdi kavē baktēriju olbaltumvielu biosintēzi, piesaistoties pie ribosomu 50s submoduļiem, un novēršot peptīda ķēdes pagarināšanos.
Son Güncelleme: 2017-04-26
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abiraterone acetate (zytiga) is converted in vivo to abiraterone, an androgen biosynthesis inhibitor.
abiraterona acetāts (zytiga) in vivo tiek pārvēsts androgēnu biosintēzes inhibitorā abirateronā.
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macrolides are bacteriostatic acting antibiotics and inhibit essential protein biosynthesis by virtue of their selective binding to bacterial ribosomal rna.
makrolīdi ir bakteriostatiskas darbības antibiotikas, kas kavē neaizvietojamo olbaltumvielu sintēzi, selektīvi piesaistoties baktēriju ribosomu rns.
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they inhibit essential protein biosynthesis by virtue of their selective binding to bacterial ribosomal rna and act by blocking the prolongation of the peptide chain.
tie kavē būtisku proteīnu biosintēzi, pamatojoties uz to selektīvo saistīšanos pie baktēriju ribosomu rns un darbojas bloķējot peptīdu ķēdes pagarināšanu.
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bh4 deficiency is a group of disorders arising from mutations or deletions in the genes encoding for one of the five enzymes involved in the biosynthesis or recycling of bh4.
bh4 deficīts ir traucējumu grupa, ko izraisa gēnu mutācijas vai izdzēšanas, kas kodē vienu no pieciem enzīmiem, kas iesaistīti bh4 biosintēzē vai reciklizācijā.
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abiraterone acetate is rapidly converted in vivo to abiraterone, an androgen biosynthesis inhibitor (see section 5.1).
abiraterona acetāts in vivo tiek ātri pārvērsts androgēnu biosintēzes inhibitorā abirateronā (skatīt 5.1. apakšpunktu).
Son Güncelleme: 2017-04-26
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posaconazole inhibits the enzyme lanosterol 14α-demethylase (cyp51), which catalyses an essential step in ergosterol biosynthesis.
posakonazols nomāc enzīmu lanosterola 14α-demetilāzi (cyp51), kas katalizē nozīmīgu ergosterola biosintēzes etapu.
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glp-1 and gip increases insulin biosynthesis and secretion from pancreatic beta cells, while glp-1 also inhibits glucagon secretion and hepatic glucose production.
glp-1 un gip pastiprina insulīna biosintēzi un izdalīšanos no aizkuņģa dziedzera bēta šūnām, turklāt glp-1 inhibē arī glikagona sekrēciju un glikozes ražošanu aknās.
Son Güncelleme: 2017-04-26
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atorvastatin lowers plasma cholesterol and lipoprotein serum concentrations by inhibiting hmg-coa reductase and subsequently cholesterol biosynthesis in the liver and increases the number of hepatic ldl receptors on the cell surface for enhanced uptake and catabolism of ldl.
4. 9 pārdozēšana
Son Güncelleme: 2011-10-23
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telavancin inhibits cell wall biosynthesis by binding to late-stage peptidoglycan precursors, including lipid ii, which prevents polymerisation of the precursor into peptidoglycan and subsequent cross-linking events.
telavancīns nomāc šūnu sienu biosintēzi, piesaistoties vēlīnā posma peptidoglikāna prekursoriem, tajā skaitā lipīdam ii, kas novērš gan prekursora polimerizāciju par peptidoglikānu, gan turpmākos krustsavienojumu gadījumus.
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mtic is spontaneously hydrolyzed to 5-amino- imidazole-4-carboxamide (aic), a known intermediate in purine and nucleic acid biosynthesis, and to methylhydrazine, which is believed to be the active alkylating species.
mtik tiek spontāni hidrolizēts līdz 5-amino-imidazola-4- karboksamīdam (aik), kas zināms kā starpprodukts purīna un nukleīnskābju biosintēzē, un līdz metilhidrazīnam, kurš ir pazīstams kā aktīvs alkilējošs savienojums.
Son Güncelleme: 2017-04-26
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