Şunu aradınız:: receptor binding domain (İngilizce - Letonca)

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receptor binding domain

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Letonca

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İngilizce

insulin receptor binding

Letonca

saistīšanās pie insulīna receptoriem

Son Güncelleme: 2017-04-26
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İngilizce

11 dopamine, and cholinergic antagonism, consistent with the receptor-binding profile.

Letonca

11 receptoriem, α1 adrenoreceptoriem un histamīna h1 receptoriem.

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İngilizce

insulin glargine is very similar to human insulin with respect to insulin receptor binding kinetics.

Letonca

saistīšanās ar insulīna receptoriem: glargīna insulīns ir ļoti līdzīgs cilvēka insulīnam saistīšanās pie insulīna receptoriem kinētikas ziņā.

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İngilizce

the receptor binding is long lasting due to the slow dissociation of telmisartan from the at1 receptor binding site.

Letonca

piesaiste receptoriem ir ilgstoša, ko nosaka telmisartāna lēnā disociācija no at1 receptorās daļas.

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İngilizce

venlafaxine and odv are very similar with respect to their overall action on neurotransmitter reuptake and receptor binding.

Letonca

venlafaxinum un odv vispārējā ietekme uz neiromediatoru atpakaļsaistīšanos un piesaisti receptoriem ir ļoti līdzīga.

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İngilizce

panitumumab binds to the ligand binding domain of egfr and inhibits receptor autophosphorylation induced by all known egfr ligands.

Letonca

panitumumabs saistās ar ligandu saistošo eafr domēnu un inhibē autofosforilēšanās receptoru, ko inducē visi zināmie eafr ligandi.

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İngilizce

the second is a glycosaminoglycan binding domain responsible for the interaction with heparin and related substances, which accelerates the inhibition of thrombin.

Letonca

otra struktūrvienība saista glikozaminoglikānu, tā ir atbildīga par mijiedarbību ar heparīnu un tam radniecīgām vielām, kas paātrina trombīna inhibīciju.

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İngilizce

animal behavioural studies with olanzapine indicated 5ht, dopamine, and cholinergic antagonism, consistent with the receptor-binding profile.

Letonca

dzīvnieku uzvedības pētījumos ar olanzapīnu tika atklāts 5ht, dopamīna un holīnerģisks antagonisms atbilstoši zāļu saistībai ar receptoriem.

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İngilizce

insulin receptor binding: in vitro studies indicate that the affinity of insulin glargine and its metabolites m1 and m2 for the human insulin receptor is similar to the one of human insulin.

Letonca

saistīšanās pie insulīna receptoriem: pētījumi in vitro liecina, ka glargīna insulīna un tā metabolītu m1 un m2 afinitāte pret cilvēka insulīna receptoriem ir līdzīga cilvēka insulīna afinitātei.

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İngilizce

most of its effects have been attributed to antagonism of adenosine receptors, both a1 and a2a subtypes, demonstrated in receptor binding assays and observed at concentrations approximating those achieved therapeutically in this indication.

Letonca

tā iedarbība lielākoties tiek piedēvēta adenozīna receptoru, gan a1, gan a2a apakštipa, antagonismam, kas pierādīts receptoru saistīšanās pētījumos un novērojot koncentrācijā, kas līdzinās tai, kas šīs indikācijas gadījumā tiek panākta terapeitiski.

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İngilizce

in combination with its subtype selective receptor-binding characteristics, with high selectivity and low affinity for the benzodiazepine type i receptor, these properties are responsible for the overall characteristics of sonata.

Letonca

sonata apvieno tādas īpašības kā apakšgrupai piemītošo selektīvo saistību ar receptoriem un augsto selektivitāti un zemo afinitāti pret benzodiazepīna i tipa atvasinājumiem.

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İngilizce

the peptibody molecule is comprised of a human immunoglobulin igg1 fc domain, with each single- chain subunit covalently linked at the c-terminus to a peptide chain containing 2 tpo receptor- binding domains.

Letonca

peptiķermenīša molekula sastāv no cilvēka imūnglobulīna igg1 fc domēna, kura atsevišķie ķēdes apakšposma c-termināli katrs kovalenti savienojas ar peptīdu ķēdi, kurai ir 2 tpo receptorus saistoši domēni.

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İngilizce

this technique may be used to probe xenobiotic interaction with specific tissue sites or cell populations as for instance in receptor binding or specific mode of action studies that may require high-resolution and high sensitivity which may not be feasible with other techniques such as whole-body autoradiography.

Letonca

šo paņēmienu var izmantot, pētot ksenobiotisko mijiedarbību ar specifiskām vietām audos vai specifiskām šūnu populācijām, piemēram, veicot tādus pētījumos par receptoru saistvietām vai specifiskiem to darbības veidiem, kuros var būt vajadzīga augsta izšķirtspēja un augsts jutīgums, ko citi paņēmieni, piemēram, visa ķermeņa autoradiogrāfija, var nenodrošināt.

Son Güncelleme: 2014-11-21
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İngilizce

however, while it may provide convenient whole body overviews of the high-capacity-low-affinity binding sites, this technique might be limited in recognising specific target sites such as receptor-binding sites where relatively high-resolution and high-sensitivity are needed for detection.

Letonca

tomēr ar šo paņēmienu var gan iegūt ērtus visa ķermeņa kopskatus attiecībā uz augstas kapacitātes un zemas afinitātes saistvietām, taču tikai ierobežoti atpazīt receptoru saistvietas un tamlīdzīgas konkrētas mērķvietas, kuru konstatēšanai ir vajadzīga samērā augsta izšķirtspēja un augsts jutīgums.

Son Güncelleme: 2014-11-21
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