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stav metabolickej aktivácie
metabolic activation condition
Son Güncelleme: 2014-11-21
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neprítomnosťexogénnej metabolickej aktivácie
absence of exogenous metabolic activation
Son Güncelleme: 2014-11-21
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neprítomnosf exogénnej metabolickej aktivácie
absence of exogenous metabolic activation
Son Güncelleme: 2014-11-21
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klastogény aktívne bez metabolickej aktivácie
clastogens active without metabolic activation
Son Güncelleme: 2014-11-21
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na rozširujúce sa bunky pôsobí testovacia látka za prítomnosti aj za neprítomnosti systému metabolickej aktivácie.
proliferating cells are treated with the test substance in the presence and absence of a metabolic activation system.
používajte obozretne u pacientov s rizikom poruchy funkcie obličiek vzhľadom na možné riziko metabolickej acidózy.
use with caution in patients with risk of renal impairment because of the possible risk of metabolic acidosis.
po perorálnom podaní sa väčšina ivakaftoru (87,8 %) eliminovala v stolici po metabolickej premene.
following oral administration, the majority of ivacaftor (87.8%) was eliminated in the faeces after metabolic conversion.
gemfibrozil 1,9-násobne zvyšuje auc kyseliny simvastatínovej, pravdepodobne v dôsledku inhibície metabolickej dráhy glukuronidácie.
gemfibrozil increases the auc of simvastatin acid by 1.9-fold, possibly due to inhibition of the glucuronidation pathway.