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this research, approved by the institutional review board of texas health resources, arlington, texas on august 23, 2013, conformed to the relevant ethical guidelines for human research. the study cohort included 70 inpatients and outpatients (46 women and 24 men) between the ages of 19–87 years (mean age, 56 years). they represented consecutive patients who attended the hospital and had serum crp and esr tests ordered together on three separate occasions during 2011. their disease may have been active or inactive at the time of sample collection. timing of the tests was determined by the attending physician(s). the second tests were performed a median of 25 days after the first and the third tests were performed a median of 29 days after the second (interquartile ranges, 6–86 and 8– 68 days, respectively). diagnoses leading to the testing are listed in table 1

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