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der er her tale om et klinisk problem i humanmedicin, hvis de macrolidresistente enterokokker ligeledes har en betydelig streptogramin b-resistens;
whereas there is a clinical problem in human medicine if the enterococci resistant to macrolides include also a major resistance to streptogramin b;
(10) den videnskabelige komité for foder anfører endvidere, at de isolerede enterokokker i tylosinresistente svin næsten alle samtidig er resistente over for erythromycin, der er et antibiotika af macrolidfamilien, som er vigtigt i humanmedicin, bl.a. ved behandlingen af åndedrætsinfektioner; den konstaterer, at selv om krydsresistensen over for lincosamider og streptograminer ikke er afprøvet af finland, er macrolidresistensen hos enterokokker ifølge litteraturen ofte eller hovedsagelig indkodet af forskellige erm-gener, der således også giver lincosamid- og streptogramin b-resistens; der er her tale om et klinisk problem i humanmedicin, hvis de macrolidresistente enterokokker ligeledes har en betydelig streptogramin b-resistens; to lincosamider anvendes klinisk i humanmedicin, nemlig lincomycin og clindamycin; to streptograminer er klinisk vigtige i humanmedicin i behandlingen som sidste udvej af vancomycinresistente enterokokker, nemlig pristinamycin og kombinationen dalfopristin/quinupristin;
(10) whereas scan also notes that tylosin-resistant enterococci isolated from pigs are almost all simultaneously resistant to erythromycin, an important macrolide antibiotic in human medicine notably in the treatment of respiratory infections; whereas it finds that, even if cross-resistance to lincosamides and streptogramins has not been tested in finland, macrolide resistance in enterococci is, according to the literature, often or mostly encoded for by different erm-genes also conferring resistance to lincosamides and streptogramin b; whereas there is a clinical problem in human medicine if the enterococci resistant to macrolides include also a major resistance to streptogramin b; whereas two lincosamides are in clinical use in human medicine, namely lincomycin and clindamycin; whereas two streptogramins are clinically important in human medicine in the treatment of last resort of vancomycin resistant enterococci, namely pristinamycin and the combination dalfopristin/quinupristin;