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chemical induction of specific locus mutations in chinese hamster cells in vitro, proc.
chemical induction of specific locus mutations in chinese hamster cells in vitro, proc.
Last Update: 2014-11-21
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however, in view of the complexities involved in these tests and the very large number of animals necessary, particularly for the specific locus test, a strong justification is needed before undertaking these studies.
vendar pa mora biti glede na zapletenost poskusov in zelo veliko število zanje potrebnih živali, zlasti za preskus specifičnega lokusa, odločitev za tovrstne študije popolnoma utemeljena.
benign bone neoplasms (osteomas) and hyperostosis seen in mice were considered a result of the activation of a mouse specific virus by fluoride ions released during the oxidative metabolism of rufinamide.
pojavljanje benignih kostnih tumorjev (osteomov) in hiperostoze, ki so jo opazili pri miših, so razlagali kot posledico aktivacije virusa, specifičnega za miši, s fluoridnimi ioni, ki se sproščajo med oksidativno presnovo rufinamida.
there are methods available to measure heritable effects in whole mammals produced by gene (point) mutations, e. g. the mouse specific locus test, to measure germ-cell mutation in the first generation, (not included in this annex), or for chromosome aberrations, e. g. the mouse heritable translocation test, (method b.25).
na voljo so metode za določitev dednih učinkov pri sesalcih, ki jih povzročijo genetske (točkaste) mutacije, na primer preskus specifičnega lokusa pri miših, s katerim se merijo mutacije mikrobnih celic na prvi generaciji (ni vključen v tej prilogi), ali metode za določitev kromosomskih nepravilnosti, na primer preskus dedne translokacije pri miših (metoda b.25).
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