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positive befunde des in-vivo-chromosomenaberrationstests deuten darauf hin, dass die prüfsubstanz im knochenmark der untersuchten spezies chromosomenaberrationen hervorruft.
positive results from the in vivo chromosome aberration test indicate that a substance induces chromosome aberrations in the bone marrow of the species tested.
Last Update: 2016-09-30
Usage Frequency: 2
Quality:
die ergebnisse des ames/salmonella-tests sowie des chromosomenaberrationstests an humanlymphozyten aus dem peripherblut (hpbl) zeigten einen positiven mutagenen effekt.
results of the ames/salmonella and human peripheral blood lymphocyte (hpbl) chromosome aberration tests showed a positive mutagenicity response.
Last Update: 2017-04-26
Usage Frequency: 10
Quality:
stavudin war bei in-vitro-untersuchungen an humanen lymphozyten, die über triphosphorylierende aktivität verfügten (und für die kein "no-effect-level" festgestellt werden konnte), in mausfibroblasten und in einem in-vivo-chromosomenaberrationstest genotoxisch.
stavudine was genotoxic in in vitro tests in human lymphocytes possessing triphosphorylating activity (in which no no-effect level was established), in mouse fibroblasts, and in an in vivo test for chromosomal aberrations.
Last Update: 2017-04-26
Usage Frequency: 8
Quality:
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