Je was op zoek naar: acetilcholinesterazs (Lithouws - Engels)

rivastigminas blokuoja acetilcholin skaidanci ferment ­ acetilcholinesterazs ir butirilcholinesterazs ­ veikl.
rivastigmine works by blocking the enzymes which break down acetylcholine: acetylcholinesterase and butyrylcholinesterase.

rivastigminas yra karbamato tipo acetilcholinesterazs ir butirilcholinesterazs inhibitorius, pagerinantis cholinerginio impulso perdavim neuronais, neleisdamas skaidyti sveik neuron isskirt acetilcholin.
rivastigmine is an acetyl-and butyrylcholinesterase inhibitor of the carbamate type, thought to facilitate cholinergic neurotransmission by slowing the degradation of acetylcholine released by functionally intact cholinergic neurones.

rivastigminas yra karbamato tipo acetilcholinesterazs ir butirilcholinesterazs inhibitorius, pagerinantis cholinerginio impulso perdavim neuronais, neleisdamas skaidyti sveik cholinergini neuron isskirt acetilcholin.
rivastigmine is an acetyl-and butyrylcholinesterase inhibitor of the carbamate type, thought to facilitate cholinergic neurotransmission by slowing the degradation of acetylcholine released by functionally intact cholinergic neurones.

rivastigmino pusins eliminacijos periodas yra apie 1 val., o acetilcholinesterazs inhibicija trunka mazdaug 9 valandas, todl, jei perdozavimas kliniskai nepasireiskia, rekomenduojama 24 valandas
as rivastigmine has a plasma half-life of about 1 hour and a duration of acetylcholinesterase inhibition of about 9 hours, it is recommended that in cases of asymptomatic overdose no further dose of rivastigmine should be administered for the next 24 hours.

rivastigmino pusins eliminacijos periodas yra apie 1 val., o acetilcholinesterazs inhibicija trunka mazdaug 9 valandas, todl, jei perdozavimas kliniskai nepasireiskia, rekomenduojama 24 valandas nevartoti rivastigmino.
as rivastigmine has a plasma half-life of about 1 hour and a duration of acetylcholinesterase inhibition of about 9 hours, it is recommended that in cases of asymptomatic overdose no further dose of rivastigmine should be administered for the next 24 hours.

sveikiems jauniems vyrams geriamoji 3 mg vaisto doz apie 40% sumazina acetilcholinesterazs (ache) aktyvum likvore per pirmsias 1, 5 valandas po vartojimo.
in healthy young men, an oral 3 mg dose decreases acetylcholinesterase (ache) activity in csf by approximately 40% within the first 1.5 hours after administration.

in vitro nustatyta, kad sis metabolitas labai silpnai slopina acetilcholinesteraz ( 10%) .
in vitro, this metabolite shows minimal inhibition of acetylcholinesterase ( 10%) .