Je was op zoek naar: kkaġunaw (Maltees - Engels)

testijiet li juru l-mekkaniżmi farmakoloġiċi li kkaġunaw l-effetti terapewtiċi;
tests demonstrating the pharmacological mechanisms underlying the therapeutic effect;

sa llum, meta studji twettqu kif għandu jkun fuq żewġ speċi nstabu sustanzi attivi li kkaġunaw malformazzjonijiet fil- bniedem kienu teratoġeniċi fl- annimali.
to date, active substances responsible for malformations in man have been found teratogenic in animals when well-conducted studies were performed in two species.

tossiċità embrijofetali ġiet osservata fil-firien u fil-fniek u kienet limitata għal dożi li kkaġunaw tossiċità sinifikanti f’annimali materni.
embryofoetal toxicity was observed in rats and rabbits and was limited to doses that caused significant toxicity in maternal animals.

dawn iċ-ċesti misjuba kkaġunaw żieda fil-ħxuna medja tal-endometriju ta’ bejn wieħed u ieħor 1.5 mm.
these cystic findings contributed to an approximate 1.5 mm increase in mean endometrial thickness.

10 fniek, abort jew reassorbiment kmieni ta ’ l- embriju kienu innotati b’ dożi li kkaġunaw tossiċità sinifikanti fl- omm, li nkludew mwiet.
in rabbits, abortion or early resorption were noted at doses causing significant maternal toxicity, including mortality.