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maturation
maduración
Last Update: 2018-02-13
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divergences from the relative germ-line sequences are typical of antigen-driven affinity maturation (tables la and 1 b), suggesting a prolonged exposure to the antigen.
las diferencias de las secuencias de la estirpe bacteriana relativa son típicas de maduración de afinidad conducida por antígenos (tablas 1a y 1 b), lo que sugiere una exposición prolongada al antígeno.
a major component of the process of affinity maturation, shm diversifies b cell receptors used to recognize foreign elements (antigens) and allows the immune system to adapt its response to new threats during the lifetime of an organism.
su función es diversificar los receptores que usa el sistema inmunitario para reconocer elementos extraños (antígeno) y permite al sistema inmune adaptar su respuesta a las nuevas amenazas que se producen a lo largo de la vida de un organismo.
activated mature b cells also possess two other remarkable, rag-independent phenomena of manipulating their own dna: so-called class-switch recombination (aka isotype switching) and somatic hypermutation (aka affinity maturation).
activated mature b cells also possess two other remarkable, rag independent, phenomena of manipulating their own dna; so-called class-switch recombination (aka isotype switching) and somatic hypermutation (aka affinity maturation).
